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Updated: Jun 27, 2026

Visualization of DNA Replication in the Vertebrate Model System DT40 using the DNA Fiber Technique
07:18

Visualization of DNA Replication in the Vertebrate Model System DT40 using the DNA Fiber Technique

Published on: October 27, 2011

CDKs通过保护Cdc6免受APC/C依赖蛋白解,促进人类细胞中的DNA复制原始授权

Niels Mailand1, John F X Diffley

  • 1Cancer Research UK London Research Institute, Clare Hall Laboratories, Hertfordshire, United Kingdom.

Cell
|September 13, 2005
PubMed
概括

循环素依赖激酶 (CDK) 通常防止DNA复制许可,但在这里稳定了Cdc6蛋白. 这种稳定允许复制前复合组合,这是细胞分裂前的关键步骤.

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