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在DMSO-d6中使用laulimalide的构造

Pahk Thepchatri1, Daniel O Cicero, Edith Monteagudo

  • 1Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA.

Journal of the American Chemical Society
|September 15, 2005
PubMed
概括

柔性微管稳定剂Laulimalide通过NAMFIS解卷确定了15种不同的形状. 这些适合体被分为五个家族,为其复杂结构和潜在的药物相互作用提供了洞察力.

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Matrix-Assisted Laser Desorption Ionization (MALDI)

Matrix-assisted laser desorption ionization (MALDI) is a powerful analytical technique used in mass spectrometry. It enables the identification and characterization of various biomolecules, including proteins, peptides, nucleic acids, and carbohydrates. MALDI is an ionization technique, widely employed in biological and medical research, as well as in fields like pharmacology and biochemistry.The analyte of interest, a biomolecule or a mixture of biomolecules, is mixed with a suitable matrix...