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使用心室辅助器件进行心肌恢复:患病率,临床特征和结果
Marc A Simon1, Robert L Kormos, Srinivas Murali
1Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Circulation
|September 15, 2005
概括
心室辅助器件 (VAD) 可以帮助患者恢复心脏功能. 桥梁到心室恢复 (BTR) 在非缺血患者中更常见,大多数患者实现长期康复.
科学领域:
- 心脏病学 心脏病学
- 机械循环支持 机械循环支持
背景情况:
- 对于心脏移植候选人来说,心室辅助器件 (VAD) 是非常重要的.
- 静脉动脉器也可能促进通往心室恢复 (BTR) 的桥梁,但预测因素和结果尚不清楚.
研究的目的:
- 在一个大型单中心队列中调查BTR的患病率,特征和结果.
- 确定BTR最成功的患者群体和条件.
主要方法:
- 在1996年至2003年间对154个成年VAD植入物的回顾性分析.
- 将患者分为缺血和非缺血组进行分类.
- 评估恢复率,支持持续时间和VAD后的长期结果.
主要成果:
- 10名患者 (6.5%) 实现了BTR.
- BTR发生在11%的非缺血患者和2.5%的缺血患者中.
- 非血清性BTR患者,特别是心肌炎和周周心肌病 (PPCM) 患者,显示持续恢复.
结论:
- 桥梁到心室恢复 (BTR) 是一个可行的选择,特别是在非缺血性心肌病,如心肌炎和PPCM.
- 双支并不排除成功的康复.
- 在急性炎症性心肌病中,应考虑使用VAD治疗BTR.
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