亚膜修复:修复缺血性 mitra 反的关键?
Frank Langer1, Filiberto Rodriguez, Saskia Ortiz
1Department of Cardiothoracic Surgery, Stanford University School of Medicine, 300 Pasteur Dr, Stanford, CA 94305, USA.
Circulation
|September 15, 2005
概括
一种新的手术技术使用接来重新定位后面的乳头肌肉 (PPM) 有效地减少了绵羊的急性缺血腹反 (IMR). 这种亚膜修复显示出作为IMR标准取消造假术的辅助措施的前景.
科学领域:
- 心血管外科心血管外科
- 医疗器械 医疗器械
- 手术技巧 手术技巧
背景情况:
- 缺血性额外外 (IMR) 经常在标准结婚整形术后持续存在,原因是环状扩张的纠正有限.
- 后面乳头肌肉 (PPM) 位移是IMR的一个关键因素,需要特别注意.
- 提出了一种针对PPM位移的新型亚膜修复技术.
研究的目的:
- 评估一种新的手术技术,以纠正后侧 papillary 肌肉 (PPM) 位移.
- 评估这项技术在减少急性缺血额头吐 (IMR) 的有效性.
- 为了确定该技术是否可以作为额头环解剖手术的辅助手段.
主要方法:
- 使用了一种带有诱导性缺血 mitrale 吐的绵羊模型.
- 放射性不透明的标记物被放置在 mitra 器官和左心室上.
- 为了重新定位PPM,使用了一种新的接技术 (STRING-1和STRING-2).
- 在紧之前和之后,通过透食管回声心脏成像来分级 mitrale regurgitation 的严重程度.
主要成果:
- 收紧STRING-1显著降低了IMR (2.0至1.2,P<0.05).
- 单独使用STRING-2并没有显著改变IMR.
- 结合的STRING-1和STRING-2也降低了IMR (2.3至1.3,P<0.05).
- STRING-1和STRING-1+2显著地重新定位了PPM基部,但没有影响关叶片运动.
结论:
- 使用STRING-1技术对PPM的基础重新定位有效地减少了急性IMR.
- 这种亚膜修复解决了PPM位移,而不依赖于环状大小.
- 这种技术可以作为一个有价值的补充剂,用于可能在取消整形后残留IMR的患者.
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