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Updated: May 11, 2026

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在3'拼接部位的突变可以通过裂变酵母中U1 snRNA的补偿基变化来抑制

C I Reich1, R W VanHoy, G L Porter

  • 1University of Illinois, Department of Biochemistry, Urbana 61801.

Cell
|June 26, 1992
PubMed
概括

与3'拼接位AG的U1小核RNA (snRNA) 配对对于酵母中高效的内子拼接至关重要. 在U1 snRNA中的补偿突变恢复了拼接,揭示了与祖先RNA拼接机制的进化联系.

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