冠状动脉的血管内超声波成像. 三层是正常的吗?
P J Fitzgerald1, F G St Goar, A J Connolly
1Cardiovascular Research Institute, University of California, San Francisco 94143.
Circulation
|July 1, 1992
概括
冠状动脉内超声波显示,冠状动脉的三层外观表明显著的内密加厚. 这种分层的外观,在年轻人中不存在,随着年龄的增长变得越来越普遍.
科学领域:
- 心血管成像 - 心血管成像
- 组织病理学 组织病理学
- 血管生物学 血管生物学
背景情况:
- 冠状动脉成像对于了解血管健康至关重要.
- 血管内超声波 (IVUS) 发现的解释需要与组织学数据的相关性.
- 早期发现血管变化是预防心血管疾病的关键.
研究的目的:
- 评估通过血管内超声波 (IVUS) 观察到的冠状动脉三层外观的意义.
- 为了将IVUS发现与青少年和成人冠状动脉的组织病理学数据相关联.
- 为了确定冠状动脉分层和内脏加厚之间的关系.
主要方法:
- 来自16名没有冠状动脉疾病史的 (13-55岁) 个体的尸体解剖心脏被检查.
- 血管内超声波 (IVUS) 影像检查是在心上冠状动脉上进行的.
- 分析了72个截面,将IVUS图像与相应的组织学截面相关联.
主要成果:
- 组织学分析显示,与无层段 (112 ± 55 微米) 相比,三层IVUS段的亲密厚度显著增加 (243 ± 105 微米).
- 178微米的内厚度值区分了分层和非分层部分.
- 患有三层动脉 (42.8±9.8岁) 的患者的平均年龄高于没有明显分层的患者 (27.1±8.5岁).
结论:
- 年轻,健康的冠状动脉壁在冠状动脉内超声波上显得均,没有明显的分层.
- 在IVUS上,三层的外观表明亲密的厚度至少为178微米.
- 三层层的外观与年龄的增长有关,并表明潜在的内变厚.
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