评估和管理喉回流
1Department of Surgery, Division of Otolaryngology, University of Wisconsin, Madison, USA. ford@surgery.wisc.edu
JAMA
|September 29, 2005
概括
喉回流 (LPR) 引起喉炎症,与GERD不同. 诊断包括症状评估和证实性测试,如阻抗和pH监测,以有效管理.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 胃肠病学 胃肠病学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 喉回流 (LPR) 是喉炎症的重要原因之一.
- 与经典胃食道逆流性疾病 (GERD) 相比,LPR呈现出明显的症状.
研究的目的:
- 概述一个评估和管理LPR案件的实际框架.
- 根据病理生理学和临床表现来区分LPR和GERD.
主要方法:
- 在PubMed和Ovid数据库中对LPR相关研究进行系统的文献搜索.
- 手动搜索关键期刊和参考清单,查找有关LPR诊断和治疗的相关研究.
主要成果:
- 慢性肺炎是由小量的反流产生的,导致局部喉症状,与GERD不同.
- 经过验证的工具,如反流症状指数和反流发现分数,有助于初步LPR诊断.
- 多通道内阻抗和pH监测为LPR事件提供了更好的诊断准确性,包括非酸性反流.
结论:
- 怀疑LPR源于暗示性病史和喉腔镜检查结果.
- 如果行为改变和PPI的3个月试验失败,则需要进行确认性研究.
- 阻抗和pH监测对于确认LPR和评估其严重程度至关重要.
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