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Updated: Jul 28, 2026

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
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Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism

Published on: July 28, 2017

晶体结构,反应性和推断的乙化过渡状态为2'-胺基替代RNA

Costin M Gherghe1, Joseph M Krahn, Kevin M Weeks

  • 1Department of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599-3290, USA.

Journal of the American Chemical Society
|September 30, 2005
PubMed
概括

核酸中的ribose 2'-amine替代物提供了结构性的洞察力. 这些2'-胺基组的化学反应揭示了核酸的灵活性和RNA和DNA的结构变化.

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