ангиотензин转化酶抑制剂:一种新的作用机制

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Updated: Jul 21, 2026

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
09:45

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors

Published on: April 27, 2017

Hongmei Peng1, Oscar A Carretero, Nikola Vuljaj

  • 1Hypertension and Vascular Research Division, Henry Ford Hospital, Detroit, MI 48202-2689, USA.

Circulation
|October 12, 2005
PubMed
概括

ангиотензин转化酶 (ACE) 抑制剂通过阻断N-乙--亚斯帕提尔-lysyl-proline (Ac-SDKP) 的分解来降低高血压中的心脏纤维化. 这种新的机制降低了炎症,细胞增殖和原沉积,提供了新的治疗见解.

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