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Updated: May 11, 2026

A Simple Alternative to Stereotactic Injection for Brain Specific Knockdown of miRNA
06:53

A Simple Alternative to Stereotactic Injection for Brain Specific Knockdown of miRNA

Published on: December 26, 2015

在体内使用"抗体"对微RNA进行沉默

Jan Krützfeldt1, Nikolaus Rajewsky, Ravi Braich

  • 1Laboratory of Metabolic Diseases, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA.

Nature
|November 1, 2005
PubMed
概括

化学工程对抗剂有效地使小鼠的内源微RNA (miRNA) 沉默,使体内功能丧失研究成为可能. 这种强大的工具展示了特定的,持久的miRNA沉默,具有潜在的治疗应用.

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