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Updated: Jun 20, 2026

Isolation of Cognate RNA-protein Complexes from Cells Using Oligonucleotide-directed Elution
10:53

Isolation of Cognate RNA-protein Complexes from Cells Using Oligonucleotide-directed Elution

Published on: January 16, 2017

人类RISC配对微RNA生物发生和转录后基因沉默

Richard I Gregory1, Thimmaiah P Chendrimada, Neil Cooch

  • 1The Wistar Institute, Philadelphia, Pennsylvania 19104, USA.

Cell
|November 8, 2005
PubMed
概括

RNA干扰利用了RNA诱导的沉默复合体 (RISC). 这项研究确定了RISC的组成,并表明它将microRNA处理与目标RNA分裂相结合,独立于ATP.

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A Complete Pipeline for Isolating and Sequencing MicroRNAs, and Analyzing Them Using Open Source Tools09:29

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