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Updated: May 10, 2026

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与α2亚单元相关的AMPK活性增加和PRKAG2心肌病变

Ferhaan Ahmad1, Michael Arad, Nicolas Musi

  • 1Department of Genetics, Harvard Medical School, Howard Hughes Medical Institute, Boston, MA, USA.

Circulation
|November 9, 2005
PubMed
概括

通过激活α2-AMPK,PRKAG2突变会导致心肌病,导致糖原的积累. 在小鼠中抑制alpha2-AMPK逆转了心脏和导电异常,确定alpha2为关键介质.

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