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探索和工程细胞表面接口接口.

Molly M Stevens1, Julian H George

  • 1Department of Materials and Institute for Biomedical Engineering, Imperial College of Science, Technology, and Medicine, Prince Consort Road, London SW7 2BP, UK. m.stevens@imperial.ac.uk

Science (New York, N.Y.)
|November 19, 2005
PubMed
概括
此摘要是机器生成的。

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科学家可以通过设计纳米级材料表面来控制细胞的行为. 这项研究审查了为组织再生和医疗植入物创建教学环境的方法.

科学领域:

  • 生物材料科学 生物材料科学
  • 细胞生物学 细胞生物学
  • 纳米技术纳米技术

背景情况:

  • 细胞反应受到各种尺度上的物理和化学线索的影响.
  • 了解这些线索对于开发先进生物材料至关重要.

研究的目的:

  • 通过纳米级表面工程来审查目前控制细胞行为的策略.
  • 突出这些工程材料在生物医学应用中的潜力.

主要方法:

  • 关于纳米级表面修饰技术的科学文献的综述.
  • 对通过材料表面图案对细胞反应进行控制的研究进行分析.

主要成果:

  • 材料表面的纳米尺度模式有效地指导细胞行为.
  • 工程表面提供精确控制细胞粘附,增殖和分化.

结论:

  • 材料表面的纳米级工程是控制细胞行为的强大工具.
  • 应用包括先进的医疗植入物和用于组织再生的教学支架.

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