与其α,β和gammac受体的双素-2的四级复合物的结构

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Production of Disulfide-stabilized Transmembrane Peptide Complexes for Structural Studies
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Production of Disulfide-stabilized Transmembrane Peptide Complexes for Structural Studies

Published on: March 6, 2013

Xinquan Wang1, Mathias Rickert, K Christopher Garcia

  • 1Howard Hughes Medical Institute, Department of Microbiology and Immunology, Stanford University School of Medicine, 299 Campus Drive, Fairchild D319, Stanford, CA 94305, USA.

Science (New York, N.Y.)
|November 19, 2005
PubMed
概括

介质素-2 (IL-2) 受体结构揭示了IL-2如何结合其α和β受体,招募共同的玛链. 这种结构洞察力解释了X-SCID突变,并有助于设计更好的IL-2疗法.

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