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Updated: Aug 14, 2026

X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050
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来自Streptomyces griseus的二-Cu2+替代氨基酶的catechol氧化酶活性

Giordano F Z da Silva1, Li-June Ming

  • 1Department of Chemistry and Institute for Biomolecular Science, University of South Florida, 4202 East Fowler Avenue, Tampa, Florida 33620-525, USA.

Journal of the American Chemical Society
|November 25, 2005
PubMed
概括

斯特雷普托米切斯灰色氨基酶有效地化和化合物. 这种酶还催化了甲基醇氧化,显示了蛋白质工程的潜力.

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Allosteric Proteins-ATCase01:19

Allosteric Proteins-ATCase

Binding sites linkages can regulate a protein's function.  For example, enzyme activity is often regulated through a feedback mechanism where the end product of the biochemical process serves as an inhibitor.
Aspartate transcarbamoylase (ATCase) is a cytosolic enzyme that catalyzes the condensation of L-aspartate and carbamoyl phosphate to  N-carbamoyl-L-aspartate. This reaction is the first step in pyrimidine biosynthesis. UTP and CTP, the end products of the pyrimidine synthesis pathway,...