患有或没有外周动脉疾病的患者的强迫性腿部疼痛
Jimmy C Wang1, Michael H Criqui, Julie O Denenberg
1University of California, School of Medicine, San Diego, CA, USA.
Circulation
|December 1, 2005
概括
炼腿部疼痛的症状各不相同,没有一种单一的疼痛类型可靠地诊断出外围动脉疾病 (PAD). 一个正常的脚-手臂指数 (ABI) 可能在1.00到1.39之间,其他因素也与腿部疼痛相关.
科学领域:
- 血管医学 血管医学
- 诊断的准确性 诊断的准确性
- 流行病学 流行病学
背景情况:
- 炼性腿部疼痛是外围动脉疾病 (PAD) 的一个关键症状.
- 运动时腿部疼痛的症状变化并未得到充分理解.
- PAD影响了人口的很大一部分.
研究的目的:
- 为了研究炼腿部疼痛特征和外围动脉疾病 (PAD) 之间的关系.
- 为了确定不同类别的腿部疼痛对PAD的诊断效用.
- 为了确定与PAD诊断之外的炼性腿部疼痛相关的因素.
主要方法:
- 来自三个队列研究的综合数据用于横截面分析.
- 评估了使用圣地亚哥音问卷的炼性腿部疼痛.
- 定义PAD使用脚-手臂指数 (ABI) <或=0.90或下肢再血管化的历史.
主要成果:
- 分析的受试者中有24.1%患有PAD.
- 在所有疼痛类别中观察到平均ABI的逐步下降,从没有疼痛到经典的音.
- 腿部低正常 (0.91-0.99) 和高正常 (>=1.40) ABIs显示疼痛率增加,表明边缘性疾病和血管硬.
- ABI与其范围内的疼痛类别有很强的相关性.
- 年龄,男性性别,糖尿病,吸烟,高BMI,心肌梗塞和先前的再血管化是腿部疼痛的独立相关因子.
结论:
- 没有任何炼性腿部疼痛类别是足够敏感或特定的,用于例行PAD诊断.
- 一个正常的ABI可能在1.00到1.39之间.
- 除ABI外,还有几种风险因素独立地与炼性腿部疼痛相关.
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