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氧化酶和多药耐药性蛋白的遗传多态性与多克索鲁比诱导的心脏毒性有关

Leszek Wojnowski1, Bettina Kulle, Markus Schirmer

  • 1Department of Pharmacology, University Mainz, D-55101 Mainz, Germany. Wojnowski@uni-mainz.de

Circulation
|December 7, 2005
PubMed
概括

药物运输和新陈代谢中的遗传变异影响了人环素诱导的心脏毒性 (ACT) 风险. 识别这些药物基因组预测因素可以帮助个性化癌症治疗并减轻心脏损伤.

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