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乌拉导向的连接连接:一种有效的策略,用于乌拉DNA糖化酶 (UNG) 抑制剂的发展

Yu Lin Jiang1, Daniel J Krosky, Lauren Seiple

  • 1Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21205, USA.

Journal of the American Chemical Society
|December 8, 2005
PubMed
概括

研究人员开发了一种新的 uracil-directed 连接器连接策略,以找到 uracil DNA 糖酶 (UNG) 的抑制剂. 这种方法迅速发现了新的小分子抑制剂,向酶.

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