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Transnuclear Mice with Pre-defined T Cell Receptor Specificities Against Toxoplasma gondii Obtained Via SCNT
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Published on: September 30, 2010

通过阿贝尔森小鼠白血病病毒直接转化3T3细胞

C D Scher, R Siegler

    Nature
    |February 27, 1975
    PubMed
    概括

    No abstract available in PubMed .

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    Forced Transdifferentiation01:28

    Forced Transdifferentiation

    Transdifferentiation, also known as lineage reprogramming, was first discovered by Selman and Kafatos in 1974 in silkmoths. They observed that the moths’ cuticle-producing cells transformed into salt-producing cells. Many such cases of natural transdifferentiation occur in organisms. In humans, pancreatic alpha cells can become beta cells. In newts, the loss of the eye’s lens causes the pigmented epithelial cells to transdifferentiate into the lens cells.
    Artificial transdifferentiation occurs...
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