相关实验视频
Updated: Jul 20, 2026
07:43
Mouse Models Of Helicobacter Infection And Gastric Pathologies
Published on: October 18, 2018
概括
雌激素可以在雄性大鼠中诱导益生素受体,但低切除术阻止了这一点. 下垂体植入物恢复了受体水平,这表明益生菌可能会诱导其自身的受体.
科学领域:
- 内分泌学 在内分泌学.
- 生殖生物学 生殖生物学
- 分子内分泌学分子内分泌学
背景情况:
- 在成年雌性老鼠肝脏中存在益生菌受体.
- 雌激素可以诱导雄性大鼠的益生菌受体.
- 下垂体切除术 (下垂体切除) 影响受体水平和反应能力.
研究的目的:
- 为了研究垂体和益生菌在调节益生菌受体表达中的作用.
- 为了确定益生菌能否诱导其自身的受体.
主要方法:
- 研究了成年雌性和雄性大鼠在各种条件下的益生菌受体水平:完好无损,缺血切除,雌激素治疗和垂体植入物.
- 测量了循环中的益生素水平.
主要成果:
- 缺血切除术减少了女性的受体水平,使男性对雌激素无反应.
- 一个垂体植入物阻止了受体降低在hypophysectomized女性.
- 下垂体植入物诱导了缺血切除的男性的益生菌受体,前面是循环中益生菌的升高.
结论:
- 下垂体激素,特别是益生菌,在调节益生菌受体表达方面发挥着至关重要的作用.
- 益生菌似乎诱导了自己的受体,建立了一个积极的反循环.
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About 48 different soluble family members of nuclear receptors are identified that can be divided into two main classes:
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