突然婴儿死亡综合征和其他怀孕的并发症
Gordon C S Smith1, Angela M Wood, Jill P Pell
1Department of Obstetrics and Gynaecology, Cambridge University, Rosie Hospital, Cambridge CB2 2SW, UK. gcss2@cam.ac.uk
Lancet (London, England)
|December 20, 2005
概括
患有突然婴儿死亡综合征 (SIDS) 的妇女更有可能出现妊娠并发症. 重复出现的怀孕问题可能会导致在随后的分娩中重复出现SIDS病例.
科学领域:
- 产科和妇科 产科和妇科
- 新生儿健康 新生儿健康
- 流行病学 流行病学
背景情况:
- 婴儿突然死亡综合征 (SIDS) 的复发是一个重大的问题,具有生物学,临床和法律影响.
- 产科并发症与增加SIDS风险有关,并且往往会在随后的怀孕中复发.
- 这项研究调查了先前SIDS与其他怀孕中的产科并发症之间的关联.
研究的目的:
- 为了确定婴儿死于SIDS的妇女是否更有可能在其他怀孕中出现产科并发症.
- 探索可能导致SIDS的妊娠并发症的复发模式.
主要方法:
- 利用相关的英国国家数据库:产科医院出院,产前死亡和死亡证明.
- 在1985年至2001年期间,分析了258,096名在苏格兰连续分娩的妇女的数据.
- 采用多变量分析来识别和解释SIDS,产科并发症和复发之间的联系.
主要成果:
- 之前有过SIDS婴儿的妇女在随后的怀孕中面临着分娩小于妊娠年龄 (OR 2.27) 和早产婴儿 (OR 2.53) 的风险增加.
- 孕期较小的母亲 (OR 1.87) 或早产婴儿 (OR 1.93) 产生的孩子有较高的SIDS风险.
- 多变量分析表明,常见的母亲风险因素和胎儿生长限制和早产的复发解释了这些关联.
结论:
- 婴儿死于SIDS的妇女在统计学上更容易在其他怀孕中出现并发症.
- 导致SIDS的妊娠并发症的复发可能部分解释了一些家庭中SIDS的复发病例.
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