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Updated: Jul 24, 2026

Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding
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Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding

Published on: September 15, 2010

确定V3环作为HIV-1 CD4中和敏感性的主要决定因素

S S Hwang1, T J Boyle, H K Lyerly

  • 1Department of Microbiology and Immunology, Duke University Medical Center, Durham, NC 27710.

Science (New York, N.Y.)
|July 24, 1992
PubMed
概括

主要人体免疫缺陷病毒1型 (HIV-1) 隔离物表现出对可溶性CD4 (sCD4) 中和的抗性,与实验室菌株不同. 艾滋病毒-1包膜蛋白的V3循环决定了组织热带性和sCD4耐药性.

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