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Updated: Jul 8, 2026

Primer Extension Capture: Targeted Sequence Retrieval from Heavily Degraded DNA Sources
15:28

Primer Extension Capture: Targeted Sequence Retrieval from Heavily Degraded DNA Sources

Published on: September 3, 2009

从元基因组学到古基因组学:猛象DNA的大规模测序

Hendrik N Poinar1, Carsten Schwarz, Ji Qi

  • 1McMaster Ancient DNA Center, McMaster University, 1280 Main Street West, Hamilton ON, L8S 4L9 Canada. poinarh@mcmaster.ca

Science (New York, N.Y.)
|December 22, 2005
PubMed
概括

研究人员从西伯利亚测序了毛猛的DNA,恢复了高比例的猛遗传物质. 这一突破为完成猛象基因组和推进古遗传学铺平了道路.

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While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.