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热量测量证据表明β-hairpin的双态展开trpzip4

Werner W Streicher1, George I Makhatadze

  • 1Department of Biochemistry and Molecular Biology, Penn State University College of Medicine, Hershey, PA 17033, USA.

Journal of the American Chemical Society
|January 5, 2006
PubMed
概括

这项研究提供了热量测量证据,证明Trpzip4,一个模型β-hairpin,经历了两种状态的展开. 这证实了其适用于研究蛋白质二次结构稳定性和折叠动态的适用性.

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