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相关概念视频

What are Membranes?01:54

What are Membranes?

A key characteristic of life is the ability to separate the external environment from the internal space. To do this, cells have evolved semi-permeable membranes that regulate the passage of biological molecules. Additionally, the cell membrane defines a cell’s shape and interactions with the external environment. Eukaryotic cell membranes also serve to compartmentalize the internal space into organelles, including the endomembrane structures of the nucleus, endoplasmic reticulum and Golgi...
Membrane Fluidity01:23

Membrane Fluidity

Cell membranes are composed of phospholipids, proteins, and carbohydrates loosely attached to one another through chemical interactions. Molecules are generally able to move about in the plane of the membrane, giving the membrane its flexible nature called fluidity. Two other features of the membrane contribute to membrane fluidity: the chemical structure of the phospholipids and the presence of cholesterol in the membrane.Fatty acids tails of phospholipids can be either saturated or...
What are Membranes?01:24

What are Membranes?

A cell's plasma membrane demarcates the cell's borders and determines the nature of its interaction with the environment. Cells exclude certain substances, take in others, and excrete some others in controlled quantities. The plasma membrane must be flexible to allow certain cells, such as red and white blood cells, to change their shape while passing through narrow capillaries. These are the more obvious plasma membrane functions. In addition, the plasma membrane's surface carries markers that...
Membrane Fluidity01:26

Membrane Fluidity

Membrane fluidity is explained by the fluid mosaic model of the cell membrane, which describes the plasma membrane structure as a mosaic of components—including phospholipids, cholesterol, proteins, and carbohydrates—that gives the membrane a fluid character.
Mosaic nature of the membrane
The mosaic characteristic of the membrane helps the plasma membrane remain fluid. The integral proteins and lipids exist as separate but loosely-attached molecules in the membrane. The membrane is a relatively...
Tissue Membranes01:27

Tissue Membranes

A tissue membrane is a thin layer of cells that covers the outside of the body, the organs, internal passageways that lead to the exterior of the body, and the lining of the moveable joint cavities. There are two basic types of tissue membranes— connective tissue and epithelial membranes.
Connective Tissue Membranes
The connective tissue membrane is formed solely from connective tissue. These membranes encapsulate organs, such as the kidneys, and line our movable joints. A synovial membrane is...
Curing Methods01:26

Curing Methods

Concrete members with a small surface-to-volume ratio are cured by oiling and moistening the forms before casting the concrete member. These forms can be left in place for a prolonged period to prevent moisture loss, and can be wetted if made of a material suitable for wetting. If the forms are removed early, the concrete member is moistened and covered with polythene sheets to maintain moisture. For large horizontal concrete surfaces exposed to dry weather, a temporary covering is suspended...

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相关实验视频

Updated: Jul 19, 2026

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification
07:32

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification

Published on: April 7, 2017

用水凝封装的脂质膜.

Tae-Joon Jeon1, Noah Malmstadt, Jacob J Schmidt

  • 1Department of Bioengineering, University of California-Los Angeles, Los Angeles, CA 90095, USA.

Journal of the American Chemical Society
|January 5, 2006
PubMed
概括

我们在聚合物水凝中稳定了脂质膜,从而实现了稳定的单分子DNA分析. 封装膜减缓了DNA转位超过100倍,增强了生物分子传感应用.

科学领域:

  • 生物物理学的生物物理.
  • 材料科学 材料科学 材料科学
  • 纳米技术纳米技术

背景情况:

  • 平面脂质膜对于研究膜蛋白和生物分子相互作用至关重要.
  • 独立的膜是不稳定的,这限制了它们在长期单分子研究中的应用.
  • α-hemolysin (aHL) 通道用于DNA分析的纳米孔传感.

研究的目的:

  • 开发一种使用聚合物凝封装稳定平面脂质膜的方法.
  • 研究封装对膜稳定性的影响及其适用于单分子测量的适用性.
  • 评估封装膜对单链DNA通过aHL通道的转位动态的影响.

主要方法:

  • 在现场光聚合被用来在聚合物水凝中封装独立的平面脂质膜.
  • 封装膜的稳定性随着时间的推移被评估.
  • 单分子测量使用集成的α-hemolysin通道蛋白进行.
  • 在封装和无凝膜中通过aHL分析了单链DNA的转位.

主要成果:

  • 封装脂质膜的稳定性至少持续了5天.
  • 聚合物水凝为嵌入的aHL蛋白质的单分子测量提供了稳定的环境.
  • 与无凝膜相比,在封装膜中通过aHL进行单链DNA转移的速度减慢了100倍以上.

更多相关视频

Self-Assembly of Hybrid Lipid Membranes Doped with Hydrophobic Organic Molecules at the Water/Air Interface
06:28

Self-Assembly of Hybrid Lipid Membranes Doped with Hydrophobic Organic Molecules at the Water/Air Interface

Published on: May 1, 2020

Accessible Silicone Chip-to-Membrane Sealing Procedure for Flexible, Reliable Bonding
06:10

Accessible Silicone Chip-to-Membrane Sealing Procedure for Flexible, Reliable Bonding

Published on: March 20, 2026

相关实验视频

Last Updated: Jul 19, 2026

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification
07:32

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification

Published on: April 7, 2017

Self-Assembly of Hybrid Lipid Membranes Doped with Hydrophobic Organic Molecules at the Water/Air Interface
06:28

Self-Assembly of Hybrid Lipid Membranes Doped with Hydrophobic Organic Molecules at the Water/Air Interface

Published on: May 1, 2020

Accessible Silicone Chip-to-Membrane Sealing Procedure for Flexible, Reliable Bonding
06:10

Accessible Silicone Chip-to-Membrane Sealing Procedure for Flexible, Reliable Bonding

Published on: March 20, 2026

  • 稳定膜促进了DNA单分子分析的增强.
  • 结论:

    • 在现场光聚合有效地稳定了聚合物水凝中的平面脂质膜.
    • 封装膜为长期单分子生物物理研究提供了强大的平台.
    • 显著减缓DNA转位对先进的DNA分析和生物分子传感有影响.
    • 这项技术有望用于生物分子传感器,膜蛋白研究和药物发现的应用.