国家心脏,肺和血液研究所的儿科循环支持计划
J Timothy Baldwin1, Harvey S Borovetz, Brian W Duncan
1Division of Heart and Vascular Diseases, The National Heart, Lung, and Blood Institute, Bethesda, MD 20892-7940, USA. baldwint@nhlbi.nih.gov
Circulation
|January 5, 2006
概括
新的儿科循环支持装置旨在克服当前短期选择的局限性. 这些针对婴儿和儿童的新系统专注于减少感染,出血和血栓栓塞的风险.
科学领域:
- 生物医学工程 生物医学工程
- 儿童心脏病学 儿童心脏病学
- 医疗器械开发 医疗器械开发
背景情况:
- 目前5岁以下儿科患者的循环支持仅限于短期的体外器械.
- 这些设备与严重的并发症有关,包括感染,出血和血栓栓塞.
- 对于婴儿和儿童的先进,可靠的循环支持解决方案存在关键需求.
研究的目的:
- 为了解决现有的儿科循环支持系统的局限性.
- 为患有心血管疾病的婴儿和儿童 (2-25公斤) 开发一系列新型设备.
- 为了尽量减少感染,出血和血栓栓塞的风险,在儿科循环支持中.
主要方法:
- 国家心脏,肺和血液研究所资助了五种不同的设备类型的开发.
- 这些包括可植入的混合流室辅助器件 (VADs) 适用于不同年龄组和大小.
- 其他发展包括集成的心肺辅助系统和轴流和脉动流的VAD.
主要成果:
- 开发了五种新的儿科循环支持装置概念.
- 这些设备旨在为婴儿和儿童提供可靠的循环支持.
- 目标是减轻与当前支持系统相关的常见并发症.
结论:
- 新的循环支持装置正在开发中,以满足儿科患者的需求.
- 这些先进的系统旨在通过减少与设备相关的并发症来改善结果.
- 这些设备的临床研究预计将于2009年开始.
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