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Updated: Jul 8, 2026

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
09:04

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells

Published on: May 22, 2014

与痛风相关的尿酸晶体激活了NALP3炎症酶

Fabio Martinon1, Virginie Pétrilli, Annick Mayor

  • 1Department of Biochemistry, University of Lausanne, Chemin des Boveresses 155, 1066 Epalinges, Switzerland.

Nature
|January 13, 2006
PubMed
概括

晶体沉积会通过激活NALP3炎症体,触发痛风和伪痛风的炎症,从而导致互白素-1β和互白素-18的产生. 这一途径对于水晶诱导的炎症反应至关重要.

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