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使用pi-allylpalladium复合物进行铁选择性蛋白质化.

S David Tilley1, Matthew B Francis

  • 1Department of Chemistry, University of California, Berkeley, 94720-1460, USA.

Journal of the American Chemical Society
|January 26, 2006
PubMed
概括

研究人员开发了一种新的催化反应,通过向氨酸残留物来修改蛋白质. 这种方法可以使水中的蛋白质功能化,产生合成脂蛋白,并提供一种新的蛋白质修饰策略.

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The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...
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