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皮肤穿透静脉部解剖手术:在冠状动脉鼻内植入装置的初始人类经验
John G Webb1, Jan Harnek, Brad I Munt
1St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada. webb@providencehealth.bc.ca
Circulation
|February 8, 2006
概括
一种用于 mitra annuloplasty 的新输血装置显示出对治疗缺血性 mitra regurgitation (MR) 的前景. 这种穿皮疗法可能为手术提供一种不那么侵入性的替代方案,在初始患者研究中减少了MR的严重程度.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 医疗器械 医疗器械
背景情况:
- 副手膜解体术是一种常见的手术治疗缺血性副手膜反 (MR).
- 目前的外科手术方法面临的局限性包括发病率,死亡率和MR的复发.
- 一种通过皮肤输送的透静管导管的器件为外科解剖整形提供了一个潜在的替代方案.
研究的目的:
- 评估一种新型的穿透静脉导管输送装置的安全性和可行性,用于皮肤穿透的 mitra 取消造形术.
- 评估该设备在慢性缺血性MR患者中减少额头骨吐的疗效.
主要方法:
- 在五名患有慢性缺血性MR的患者中,在冠状动脉鼻中进行了皮透静脉植入一个解剖整形装置.
- 评估了设备植入成功和程序安全.
- 在基线和植入后的随访期间,对 mitrale regurgitation 的严重程度进行了分级.
主要成果:
- 在5名患者中,有4名患者实现了成功的植入.
- 基线MR (等级3.0+/-0.7) 在植入后降低到等级1.6+/-1.1.
- 在4个植入的设备中,有3个设备在28至81天之间发生了设备桥分离;没有报告与设备相关的并发症.
结论:
- 可行的是通过皮肤植入一只 mitra 取缔器械.
- 初步发现表明,减少MR严重性的潜在好处.
- 进一步调查皮肤穿透静脉部解体术是合理的,因为这是一个不那么侵入性的选择.
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