中心和大动脉环状化与全身化动脉样硬化高度相关
Matthew A Allison1, Philip Cheung, Michael H Criqui
1Department of Family and Preventive Medicine, University of California San Diego, San Diego, California, USA. mallison@ucsd.edu
Circulation
|February 8, 2006
概括
动脉动脉硬化与心脏门的化有关. 这项研究发现,大动脉和门动脉的化强烈预测大动脉环状化.
科学领域:
- 心血管医学 心血管医学
- 放射学 放射学是一门学科.
- 动脉样硬化研究 动脉样硬化研究
背景情况:
- 动脉样硬化是疑似导致膜化的原因之一.
- 膜化,特别是大动脉和心肌环状化,会影响无症状患者.
- 传统的风险因素本身并不能完全解释膜化.
研究的目的:
- 调查多个血管床中的动脉样硬化和大动脉或心心环状化之间的关联.
- 确定这种关联是否独立于传统的心血管风险因素.
主要方法:
- 电子束计算断层扫描 (EBCT) 用于评估5个血管床和大动脉和心心环中的化.
- 包括1242名没有临床冠状动脉心脏病的无症状患者.
- 根据年龄,性别和心血管疾病风险因素调整后的统计分析.
主要成果:
- 24%的患者出现了大动脉环状化,8%的患者出现了 mitra环状化.
- 年龄和高血压是唯一与环状化独立相关的传统风险因素.
- 胸腔大动脉的化与大动脉环状化有关 (OR=3.9),而腹部大动脉的化与状环状化有关 (OR=5.1).
- 腹腔大动脉 (OR=2.0) 和腹腔动脉 (OR=1.8) 的化预测了大动脉环状化,胸腔大动脉化预测了中枢环状化 (OR=1.4).
结论:
- 这些发现支持这样一个假设,即心肌和大动脉环状化与血管系统其他部位的动脉样硬化有关.
- 不同血管床中的动脉样硬化负担是膜环状化的重要预测因素.
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