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细胞内膜网膜应激激活了CREBH的分裂,从而诱导了全身炎症反应

Kezhong Zhang1, Xiaohua Shen, Jun Wu

  • 1Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, MI 48109, USA.

Cell
|February 14, 2006
PubMed
概括

肝脏特异性转录因子CREBH在细胞内网膜 (ER) 应激过程中被分裂. 这种分裂激活了急性阶段反应 (APR) 基因,将ER压力与炎症联系起来.

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