从常规黑白回声心脏图像中新型的斑点追踪辐射菌株来量化异步并预测对心脏再同步治疗的反应
Matthew S Suffoletto1, Kaoru Dohi, Maxime Cannesson
1The Cardiovascular Institute, University of Pittsburgh, Pittsburgh, PA 15213-2582, USA.
Circulation
|February 16, 2006
概括
新型心声回声学斑点跟踪准确地预测心脏再同步治疗 (CRT) 的反应. 这种方法量化了机械异步,改善了CRT患者的选择,并优化了结果.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 生物医学工程 生物医学工程
背景情况:
- 机械失同是预测患者对心脏再同步治疗 (CRT) 反应的关键因素.
- 目前用于评估异步的方法可能无法完全捕捉心脏力学细微差别.
- 新的心声回声技术为改善机械失调的量化提供了潜力.
研究的目的:
- 调查新型回声心脏图像斑点跟踪用于量化机械失调的实用性.
- 确定斑点追踪是否可以预测CRT的即时和长期反应.
- 为了评估从speckle-tracking获得的异步与传统措施之间的相关性.
主要方法:
- 斑点跟踪应用于例行中腹短轴回声心脏图像,以计算辐射应变.
- 通过测量标准心肌段中峰值辐射应变的时间来量化异步.
- 基线异步对CRT反应的预测能力使用灵敏度和特异性分析进行了评估.
主要成果:
- 斑点跟踪衍生的异步与组织多普勒测量有很强的相关性 (r=0.94,P<0.001).
- 基线辐射失同预测了CRT后的即时中风体积增加,灵敏度为91%,特异性为75%.
- 它还预测了长期喷射分数的改善,灵敏度为89%,特异性为83%.
结论:
- 斑点追踪辐射应变是量化心脏机械失调的一个可行的方法.
- 这种技术有效地预测了对CRT的即时和长期反应.
- 斑点跟踪在指导CRT治疗中具有显著的临床应用潜力.
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