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Preparation and Respirometric Assessment of Mitochondria Isolated from Skeletal Muscle Tissue Obtained by Percutaneous Needle Biopsy11:27

Preparation and Respirometric Assessment of Mitochondria Isolated from Skeletal Muscle Tissue Obtained by Percutaneous Needle Biopsy

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Methods for biopsy of Vastus lateralis, preparation of purified mitochondria, and respirometric profiling are described. The use of small muscle volume makes this technique suitable for clinical research...
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In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses09:31

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

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Optical coherence tomography (OCT) is a high resolution imaging technique that allows analysis of tissue specific optical properties providing the means for tissue differentiation. We developed needle based OCT, providing real-time imaging combined with on-the-spot tumor differentiation. This publication describes a method for percutaneous, needle based OCT of renal...
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Three-Dimensional Printing Guide Template Assisted Percutaneous Vertebroplasty (PVP)05:39

Three-Dimensional Printing Guide Template Assisted Percutaneous Vertebroplasty (PVP)

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Herein, we present a three-dimensional printing guide template for percutaneous vertebraplasty. A patient with a T11 vertebral compression fracture was selected as a case...
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A Two-Step Method for Percutaneous Transhepatic Choledochoscopic Lithotomy03:56

A Two-Step Method for Percutaneous Transhepatic Choledochoscopic Lithotomy

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This "two-step method" significantly improved the success rate of percutaneous transhepatic choledochoscopy and achieved a better prognosis of intrahepatic and extrahepatic...
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Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

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This protocol demonstrates in detail how to perform fully endoscopic mitral valve surgery (EMS) with percutaneous cannulation of the groin vessels, using a percutaneous plug-based vascular closure device. Fundamental steps and useful instructions are described in detail for each step.
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Wet Beveling of Microinjection Needles Utilizing Constant Air Pressure for Feedback on Needle Opening06:00

Wet Beveling of Microinjection Needles Utilizing Constant Air Pressure for Feedback on Needle Opening

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This protocol describes the assembly of a pneumatic system for the delivery of pressurized air to a needle during the process of needle beveling. The protocol further describes the beveling process for creating sharp microinjection needles and how to gauge the relative opening size of the...
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相关实验视频

Updated: Jul 6, 2026

Oral Bacterial Infection and Shedding in Drosophila melanogaster
09:32

Oral Bacterial Infection and Shedding in Drosophila melanogaster

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感染基因组学:从宿主基因组对传染病的洞察.

Paul Kellam1, Robin A Weiss

  • 1MRC/UCL Centre for Medical Molecular Virology, Division of Infection & Immunity, University College London, London W1T 4JF, UK.

Cell
|February 25, 2006
PubMed
概括

这项研究使用宿主基因组探索宿主-病原体相互作用,这一领域被称为感染基因组学. 这种方法提供了新的诊断和治疗策略,并增强了对细胞功能的理解.

科学领域:

  • 基因组学就是基因组学.
  • 微生物学 微生物学
  • 免疫学 免疫学 免疫学

背景情况:

  • 人类后基因组时代为了解宿主-病原体相互作用提供了基础.
  • 宿主基因组越来越被认为是研究传染病的关键.

研究的目的:

  • 为了强调"感染基因组学"方法的意义.
  • 讨论宿主基因组分析在诊断和治疗方面的潜力.
  • 探索宿主基因组在理解正常细胞功能中的作用.

主要方法:

  • 在病原体相互作用的背景下分析宿主基因组数据.
  • 审查当前的文献和研究感染基因组学.

主要成果:

  • 关于宿主-病原体相互作用,已经获得了大量的知识.
  • 感染基因组学方法在研究中被证明是有价值的.

结论:

  • 感染基因组学为诊断和治疗方面的进步提供了有希望的途径.
  • 对正常细胞功能的进一步洞察可以从宿主基因组研究中得出.

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Oral Bacterial Infection and Shedding in Drosophila melanogaster
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Automated, High-Throughput Detection of Bacterial Adherence to Host Cells
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Automated, High-Throughput Detection of Bacterial Adherence to Host Cells

Published on: September 17, 2021