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德斯莫格林-2基因的突变与心律失常的右心室心肌病相关

Kalliopi Pilichou1, Andrea Nava, Cristina Basso

  • 1Department of Biology, University of Padua Medical School, Padua, Italy.

Circulation
|March 1, 2006
PubMed
概括

德斯莫格林-2 (DSG2) 基因的突变与心律失常性右心室心肌病 (ARVC) 相关,这是一种涉及纤维脂肪组织替代的心脏病. 这项研究在10%的ARVC患者中发现了DSG2突变,突出显示了这种遗传性疾病中的desmosomal缺陷.

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