怀孕期间急性心肌梗塞:美国一项基于人口的研究
Andra H James1, Margaret G Jamison, Mimi S Biswas
1Division of Maternal-Fetal Medicine, Duke University Medical Center, Durham, NC 27710, USA. andra.james@duke.edu
Circulation
|March 15, 2006
概括
与怀孕相关的急性心肌梗塞很少见,但具有显著的风险,特别是在老年妇女中. 关键的危险因素包括高血压,血栓形成症,糖尿病,吸烟和母亲的晚年.
科学领域:
- 心血管医学 心血管医学
- 产科和妇科 产科和妇科
- 公共卫生 公共卫生
背景情况:
- 怀孕期间急性心肌梗塞 (AMI) 是一种罕见但严重的并发症.
- 了解它的发病率,死亡率和风险因素对于母亲健康至关重要.
- 怀孕与三至四倍的AMI风险增加有关.
研究的目的:
- 确定美国与怀孕相关的急性心肌梗塞的发病率,死亡率和危险因素.
- 为了确定在怀孕期间增加AMI风险的特定疾病和产科并发症.
主要方法:
- 从2000年至2002年使用了全国住院患者样本 (NIS) 数据库.
- 分析了与怀孕相关的分泌物,诊断为急性心肌梗塞.
- 采用多变量物流回归来识别重大风险因素.
主要成果:
- 与怀孕有关的AMI的发病率为每10万分娩6.2例,病例死亡率为5.1%.
- 显著的危险因素包括高血压,血栓,糖尿病,吸烟,输血,产后感染,以及30岁及以上的年龄.
- 与20岁以下的女性相比,40岁以上的女性患AMI的几率高出30倍.
结论:
- 与怀孕相关的AMI并不常见,但具有相当大的风险.
- 可修改的风险因素,如高血压,糖尿病和吸烟显著增加了AMI的可能性.
- 针对这些风险因素可能会降低与怀孕相关的心肌梗塞的发生率.
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