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Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes
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Published on: November 1, 2012

CAP-DNA复合体的晶体结构:DNA被曲了90度

S C Schultz1, G C Shields, T A Steitz

  • 1Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511.

Science (New York, N.Y.)
|August 30, 1991
PubMed
概括

晶体结构显示,大肠杆菌的催化剂基因激活蛋白 (CAP) 通过特定的基对曲线将DNA曲90度. 这种DNA曲和蛋白质-DNA相互作用是转录激活的关键.

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