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Updated: Jul 9, 2026

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1
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Published on: August 24, 2015

简单疹病毒在人类纤维细胞中的光激活

E K Wagner, M Rice, B M Sutherland

    Nature
    |April 17, 1975
    PubMed
    概括

    No abstract available in PubMed .

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    Herpes simplex type 1 (HSV‑1) is a widespread pathogen responsible for orolabial lesions. It is an enveloped, double-stranded DNA (dsDNA) virus belonging to the family Herpesviridae. Once the virus infects a host cell, its double‑stranded DNA genome is delivered into the nucleus, where a coordinated cascade of immediate‑early, early, and late gene expression directs viral DNA replication, structural protein synthesis, and virion assembly. After primary infection of epithelial cells, HSV-1...