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相关概念视频

Self-Concept01:19

Self-Concept

Self-concept is the cognitive and emotional understanding individuals hold about their identity. It evolves through various developmental stages, beginning in infancy and maturing as children grow. This concept influences how individuals perceive their abilities, interact with others, and manage challenges throughout life.
Infancy and Emerging Recognition
During infancy, self-concept is virtually nonexistent. Babies do not distinguish themselves as separate entities and often mistake their...
Understanding Self-Concept01:20

Understanding Self-Concept

The self-concept encompasses individuals' beliefs about themselves, structured through cognitive frameworks known as self-schemas. These schemas function as mental representations of specific traits or behaviors, influencing how self-relevant information is perceived, processed, and remembered. For example, individuals who are schematic for body weight are more likely to interpret routine experiences—such as dining out or shopping—through the lens of that trait. Conversely, those aschematic for...
Self Within Cultural Contexts01:30

Self Within Cultural Contexts

Cultural frameworks for understanding the self are often categorized into two broad orientations: individualism and collectivism. These paradigms influence how people define themselves, relate to others, and interpret their social worlds. Each orientation offers distinct perspectives on autonomy, responsibility, and the role of the individual within a community.Individualistic CulturesIn individualistic cultures like North America and Western Europe, identity is understood as autonomous and...
Personal Identity01:25

Personal Identity

Personal identity is the deeply felt sense of self that individuals cultivate over time, intricately woven from intrinsic qualities they consider essential to their existence—qualities such as morality, intelligence, and friendliness. These attributes serve as vital internal benchmarks, guiding individuals in evaluating whether their actions resonate with their true selves.When personal identity takes center stage in one's life, individuals often emphasize their distinctiveness, highlighting...
Self-Presentation01:25

Self-Presentation

Self-presentation is a fundamental aspect of social interaction, shaping both how others perceive individuals and how they view themselves. This dynamic process influences behaviors in various social settings, often leading people to adjust their appearance, speech, and demeanor to align with their desired identity. While self-presentation can be deliberate or unconscious, it plays a critical role in interpersonal relationships and self-perception.Forms of Self-PresentationSelf-presentation can...
Self-Discrepancy and Its Effects01:29

Self-Discrepancy and Its Effects

Self-discrepancy theory explains how people compare their actual self to their ideal and ought selves and how mismatches between these self-guides can lead to emotional distress. Developed by E. Tory Higgins, the theory distinguishes among three components of self-concept: the actual self, the ideal self, and the ought self. These refer respectively to how individuals perceive themselves, how they aspire to be, and how they believe they are obligated to be. Emotional well-being, self-esteem,...

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相关实验视频

Updated: Jul 20, 2026

Creating Virtual-hand and Virtual-face Illusions to Investigate Self-representation
06:53

Creating Virtual-hand and Virtual-face Illusions to Investigate Self-representation

Published on: March 1, 2017

关于自我复杂性的问题

Rudensky AYu1, S Rath, P Preston-Hurlburt

  • 1Section of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06510.

Nature
|October 27, 1991
PubMed
概括

一个新的抗体,Y-Ae,识别了与MHCII类分子结合的特定自我. 这一发现表明,在T细胞选择过程中呈现的自我的种类有限.

科学领域:

  • 免疫学 免疫学 免疫学
  • 分子生物学分子生物学
  • 细胞生物学 细胞生物学

背景情况:

  • 由自我主要基因相容性复合体 (MHC) 分子呈现的自我在胸腺内T细胞发育中起着至关重要的作用.
  • 阳性和阴性T细胞选择都受到这些自我-MHC相互作用的影响.
  • 了解自我的性质和表现是解读免疫系统调节的关键.

研究的目的:

  • 为了识别和描述由MHCII类分子呈现的特定自我.
  • 研究这种自我在T细胞选择过程中的作用.
  • 为了确定MHCII类分子在抗原呈现细胞上呈现的自我的复杂性.

主要方法:

  • 开发和应用一种新的MHCII类受限制单克隆抗体Y-Ae.
  • 使用Y-Ae检测和量化MHCII类结合的自我.
  • 对Y-Ae结合抗原呈现细胞和胸膜上皮细胞的分析.

主要成果:

  • Y-Ae抗体特别检测一种主要的自我与MHCII类分子结合.
  • 在自我抗原呈现细胞上,Y-Ae与大约12%的相关MHCII类分子结合.
  • 检测到的自我是从MHC分子中化出来的几个主要中的一种,表明复杂性有限.

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Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties
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Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties

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A Modified Mirror Test as a Visual Guide for the Self-awareness Trait in Wild Antarctica Penguins, Pygoscelis adeliae
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A Modified Mirror Test as a Visual Guide for the Self-awareness Trait in Wild Antarctica Penguins, Pygoscelis adeliae

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相关实验视频

Last Updated: Jul 20, 2026

Creating Virtual-hand and Virtual-face Illusions to Investigate Self-representation
06:53

Creating Virtual-hand and Virtual-face Illusions to Investigate Self-representation

Published on: March 1, 2017

Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties
12:55

Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties

Published on: September 27, 2020

A Modified Mirror Test as a Visual Guide for the Self-awareness Trait in Wild Antarctica Penguins, Pygoscelis adeliae
04:51

A Modified Mirror Test as a Visual Guide for the Self-awareness Trait in Wild Antarctica Penguins, Pygoscelis adeliae

Published on: July 8, 2025

  • Y-Ae染色与负选择相关的抗原呈现细胞,但与积极选择相关的胸膜皮层上皮细胞并非如此.
  • 结论:

    • 由自身MHCII类分子在足以信号CD4T细胞的水平上呈现的自我具有有限的复杂性.
    • 自我的差异表达:自我MHCII类复合物可能对内性T细胞选择至关重要.
    • Y-Ae抗体为研究自我呈现和T细胞选择提供了有价值的工具.