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Updated: Jul 9, 2026

RNAi Mediated Gene Knockdown and Transgenesis by Microinjection in the Necromenic Nematode Pristionchus pacificus
06:57

RNAi Mediated Gene Knockdown and Transgenesis by Microinjection in the Necromenic Nematode Pristionchus pacificus

Published on: October 16, 2011

在非人类灵长类动物中,RNAi介导的基因沉默

Tracy S Zimmermann1, Amy C H Lee, Akin Akinc

  • 1Alnylam Pharmaceuticals Inc., 300 Third Street, Cambridge, Massachusetts 02142, USA. tzimmermann@alnylam.com

Nature
|March 28, 2006
PubMed
概括

在脂质体中小干扰RNA (siRNA) 的系统输送有效地使非人类灵长类动物的阿波利波蛋白B (ApoB) 沉默. 这种RNA干扰疗法证明了强效,持久的基因沉默和降低胆固醇水平,支持其治疗潜力.

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Rearing and Double-stranded RNA-mediated Gene Knockdown in the Hide Beetle, Dermestes maculatus09:57

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