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的摄入量和代谢综合征的发病率在年轻成年人中.

Ka He1, Kiang Liu, Martha L Daviglus

  • 1Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. kahe@northwestern.edu

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|March 29, 2006
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概括

年轻人的较高摄入量与患代谢综合征的风险降低有关. 这种饮食矿物质可能在预防这种疾病方面发挥关键作用.

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科学领域:

  • 营养科学 营养科学
  • 流行病学 流行病学
  • 预防医学 预防医学

背景情况:

  • 摄入量可能与降低高血压和2型糖尿病的风险有关.
  • 更高的摄入量可能会改善脂质特征,降低甘油三和增加HDL胆固醇.
  • 对代谢综合征发生的长期影响需要进一步研究.

研究的目的:

  • 调查摄入量与代谢综合征发生率之间的纵向关联.
  • 检查摄入量与代谢综合征的各个组成部分之间的关系.
  • 评估对年轻成年人禁食胰岛素水平的影响.

主要方法:

  • 一项前性队列研究,涉及4637名年轻成年人 (18-30岁) 在基线没有代谢综合征或糖尿病.
  • 评估饮食摄入量,包括,使用定量性食物频率问卷.
  • 在15年的随访期间,使用国家胆固醇教育计划/成人治疗小组III标准诊断了代谢综合征.

主要成果:

  • 在摄入量和代谢综合征发病率之间观察到显著的反向关联.
  • 摄入量最高四分之一的参与者与最低四分之一相比,代谢综合征的风险降低了31% (HR 0.69,95% CI 0.52-0.91).
  • 对于个体代谢综合征成分和禁食胰岛素水平,无论性别和种族,也发现了逆关系.

结论:

  • 年轻成人摄入较高的与患代谢综合征的风险降低有关.
  • 适当的摄入量可能是防止代谢综合征发展的保护因素.
  • 这些发现强调了食对年轻成年人的代谢健康的重要性.