新生儿持续负压通风后的结果:后续评估评估
Katherine Telford1, Lorraine Waters1, Harish Vyas2
1School of Human Development, University of Nottingham, Nottingham, UK.
Lancet (London, England)
|April 4, 2006
概括
长期跟踪治疗持续负额外胸压 (CNEP) 的婴儿时,死亡或残疾风险没有增加. 接受CNEP治疗的儿童在童年后期表现更好,智商和神经心理学得分更好.
科学领域:
- 新生儿医学 新生儿医学
- 儿科神经学 儿科神经学
- 呼吸系统生理学 呼吸系统生理学
背景情况:
- 以前对新生儿呼吸困扰综合征持续负额外胸部压力 (CNEP) 的试验引起了人们的担忧.
- 与标准治疗相比,CNEP的长期后果需要调查.
研究的目的:
- 评估新生儿接受CNEP治疗的儿童的长期神经结果,认知功能和残疾.
- 为了确定CNEP是否与童年后期不良结果有关.
主要方法:
- 从最初的随机试验中对133名幸存者 (9-15岁) 的门诊评估.
- 由儿科医生和心理学家管理的标准化神经,认知和残疾测试.
- 对65个完整对和未配对数据的分析,主要结果是死亡或严重残疾.
主要成果:
- 在CNEP和标准治疗组之间,主要结果 (死亡或严重残疾) 没有显著差异.
- 全智商得分相似,但CNEP组表现出显著更高的性能智商 (平均差异6.8分).
- 神经心理测试显示,CNEP组的语言生产和视觉空间技能得分明显更高.
结论:
- 新生儿CNEP与童年后期较差的长期结果无关.
- 新生儿不良后果的小差异并没有转化为长期的不利影响.
- 新生儿干预的未来研究应优先考虑长期结果评估.
相关概念视频
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Critical Guidelines for Assessing Ventilation:
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Equipment Required
Equipment Required


