成年人的发病
John S Duncan1, Josemir W Sander1, Sanjay M Sisodiya1
1Department of Clinical and Experimental Epilepsy, Institute of Neurology UCL, Queen Square, London WC1N 3BG, UK and The National Society for Epilepsy, Chalfont St Peter, UK.
是一种常见的大脑疾病,原因和表现各异,影响所有年龄段. 神经成像和药物遗传学的进步为个性化治疗和对抗性的潜在治疗提供了希望.
科学领域:
- 神经学 神经学
- 遗传学 是一个遗传学.
- 神经科学是一个神经科学.
背景情况:
- 是一种常见的,严重的脑部疾病,其原因和表现各异,影响所有年龄组.
- 虽然儿童发病率已经下降,但老年发病率正在上升.
- 单一性是罕见的;常见的是受遗传学和环境影响的复杂特征.
研究的目的:
- 审查当前对病病因,诊断和治疗的理解.
- 为突出神经成像和神经生理学在诊断方面的进展.
- 探索管理的新兴治疗策略.
主要方法:
- 临床诊断和神经生理学研究.
- 先进的大脑成像技术用于识别结构和功能原因.
- 审查当前抗药物的疗效和药物遗传学研究.
主要成果:
- 的诊断仍然是临床的,由神经生理学和先进的大脑成像支持.
- 目前的抗药物在60-70%的患者中是有效的,但不会改变潜在疾病.
- 药物遗传学显示出个性化治疗的前景.
- 神经外科为耐火焦点提供了潜在的治疗方法.
结论:
- 治疗正在随着个性化医疗方法的发展而发展.
- 未来的治疗方法可能包括预测发作,向治疗和再生医学.
- 继续在遗传学,成像和新疗法方面的研究对于改善的结果至关重要.
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