盆腔炎症疾病. 盆腔炎症疾病. 关键的治疗问题和选择
H B Peterson1, C K Walker, J G Kahn
1Division of Reproductive Health, Centers for Disease Control, Atlanta, GA 30333.
JAMA
|November 13, 1991
概括
对盆腔炎症疾病 (PID) 的最佳抗菌疗法涉及由于其多微生物性质而涉及广泛的组合疗法. 虽然有效治疗,但预防长期并发症的数据有限,这表明住院治疗可能是谨慎的.
科学领域:
- 传染性疾病 传染性疾病
- 妇科 妇科 妇科 妇科
- 药理学 药理学是指药理学的学科.
背景情况:
- 盆腔炎症 (PID) 是一种多微生物感染,需要有效的抗微生物治疗.
- 最佳的治疗策略对于管理PID和预防其后果至关重要.
研究的目的:
- 审查目前关于盆腔炎症疾病 (PID) 最佳抗菌疗法的数据.
- 为治疗PID的临床医生解决关键的治疗考虑因素.
主要方法:
- 自1985年以来发表的研究的系统审查,包括那些为1989年CDC性传播疾病治疗指南提供信息的研究.
- 使用与PID和治疗相关的术语进行MEDLINE搜索,并补充了文献综述.
- 纳入标准集中在评估抗菌素治疗方案对PID治疗有效性的研究上.
主要成果:
- 广谱组合抗菌疗法在PID的临床和微生物治疗方面表现出高的疗效.
- 即使在涉及管卵巢的病例中,也可以获得有效的治疗.
- 关于预防PID长期后续症的最佳治疗方法的数据有限.
结论:
- 没有单一的抗微生物药物能够充分覆盖所有导致PID的病原体.
- 组合疗法在临床上是有效的,但关于预防晚期后果的不确定性仍然存在.
- 对于PID患者,特别是那些希望未来生育的人,应该考虑住院治疗,所有性伴侣都需要治疗.
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