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Updated: Jun 7, 2026

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含有JmjC的H3K9脱甲基酶JHDM2A促进了由雄激素受体进行转录激活

Kenichi Yamane1, Charalambos Toumazou, Yu-ichi Tsukada

  • 1Howard Hughes Medical Institute, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Cell
|April 11, 2006
PubMed
概括

研究人员确定了JHDM2A,这是一种新的基因组脱甲基酶,可以从基因组H3 lysine 9 (H3K9) 中去除甲基组. 这种酶通过逆转H3K9甲基化,对激素依赖基因激活至关重要.

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