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Regulation of Hormone Secretion
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在caspase-12缺乏的小鼠中增强了细菌清除和败血症耐药性

Maya Saleh1, John C Mathison, Melissa K Wolinski

  • 1Department of Cellular Immunology, La Jolla Institute for Allergy and Immunology, San Diego, California 92121, USA.

Nature
|April 21, 2006
PubMed
概括

缺乏caspase-12的小鼠通过更有效地清除细菌感染,增加了对败血症和败血症休克的抵抗力. 卡斯巴-12通常会抑制免疫反应,因此在这种情况下,其缺席是有益的.

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