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Updated: Jul 6, 2026

Subcloning Plus Insertion (SPI) - A Novel Recombineering Method for the Rapid Construction of Gene Targeting Vectors
09:02

Subcloning Plus Insertion (SPI) - A Novel Recombineering Method for the Rapid Construction of Gene Targeting Vectors

Published on: January 8, 2015

一个远端增强子和一个超保守的外子是由一个新型的逆位子衍生出来的

Gill Bejerano1, Craig B Lowe, Nadav Ahituv

  • 1Center for Biomolecular Science and Engineering, University of California Santa Cruz, Santa Cruz, California 95064, USA. jill@soe.ucsc.edu

Nature
|April 21, 2006
PubMed
概括

高度保存的脊椎动物基因组区域起源于古代的Sarcopterygian短间隔重复元素 (SINEs). 这些4亿多年前活跃的回形子被抽取到调节元件中,并交替拼接出外形子,揭示了它们的进化起源.

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