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Updated: Jan 14, 2026

In Vivo CRISPR/Cas9 Screening to Simultaneously Evaluate Gene Function in Mouse Skin and Oral Cavity
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在人类胚胎干细胞中通过Polycomb控制发育调节剂

Tong Ihn Lee1, Richard G Jenner, Laurie A Boyer

  • 1Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA.

Cell
|April 25, 2006
PubMed
概括

聚合体抑制复合体2 (PRC2) 结合了人类胚胎干细胞中的关键发育基因,抑制它们以保持多能性. 这些基因在分化过程中被激活,突出显示PRC2.

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