一个新的反向虫状细胞系统:在有机液体中混合了胆盐和胆素
Shih-Huang Tung1, Yi-En Huang, Srinivasa R Raghavan
1Department of Chemical and Biomolecular Engineering, University of Maryland, College Park, Maryland 20742-2111, USA.
Journal of the American Chemical Society
|April 28, 2006
概括
研究人员发现了一种新方法,利用有机液体中的胆盐和乙酸制造逆虫状菌体. 这通过形成纠的菌根网络,显著提高了流体粘度.
科学领域:
- 合体和表面科学科学
- 材料化学 材料化学
- 类风病学 类风病学 类风病学
背景情况:
- 逆虫状微粒通常在非极性溶剂中与水一起形成.
- 有机液体中的莱西溶液通常具有低粘度.
- 控制菌形成是调整流体性质的关键.
研究的目的:
- 开发一种新的方法,在没有水的情况下形成反向的虫状菌体.
- 调查胆汁盐在菌形成和流体风学中的作用.
- 了解微粒结构和散装流体特性之间的关系.
主要方法:
- 在非极性有机液体 (环素,n-decane) 中添加微量胆汁盐 (脱氧化酸盐) 到莱西丁溶液中.
- 风湿学测量以确定粘度的变化.
- 小角度中子散射 (SANS) 实验以确认菌生长.
主要成果:
- 使用胆汁盐和莱西丁建立了一个形成逆虫状菌体的新途径.
- 胆盐,由于它们的面部两性,诱导了莱西丁分子的纵向聚合.
- 由于纠的反转菌根网络,莱西丁有机盐的粘度增加了超过5个数量级.
- 胆汁盐与莱西丁的摩尔比被确定为控制粘度增强的关键因素.
结论:
- 胆盐可以作为有效的结构指导剂,在有机介质中逆转菌形成,取代对水的需求.
- 短暂的,纠的网络的形成,反向的虫状菌根极大地改变了莱西溶液的粘弹性特性.
- 这项工作为设计和控制有机盐的质行为通过定制的状结构提供了一条新的途径.
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