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Updated: Jul 11, 2026

Nuclear Magnetic Resonance Spectroscopy for the Identification of Multiple Phosphorylations of Intrinsically Disordered Proteins
12:47

Nuclear Magnetic Resonance Spectroscopy for the Identification of Multiple Phosphorylations of Intrinsically Disordered Proteins

Published on: December 27, 2016

不统一采样的双TROSY hNcaNH实验用于NMR对大型蛋白质的顺序赋值

Dominique P Frueh1, Zhen-Yu J Sun, David A Vosburg

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts 02115, USA

Journal of the American Chemical Society
|April 28, 2006
PubMed
概括

这项研究引入了针对蛋白质NMR共振赋值的新型hNcaNH实验,提高了灵敏度和分辨率. 这些改进的方法克服了大型蛋白质的局限性,使得更快,更准确的分配成为可能.

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