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Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
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转化生长因子-β诱导了T(H) 17血统的发展

Paul R Mangan1, Laurie E Harrington, Darrell B O'Quinn

  • 1Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35294-2170, USA.

Nature
|May 2, 2006
PubMed
概括

转化生长因子-β (TGF-β) 通过上调IL-23R对T-辅助者-17 (T(H) 17细胞发育至关重要. 这种细胞因子信号通路是对细胞外细菌的适应性免疫的关键,并与自身免疫性疾病有关.

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